To improve the error detection efficiency and the benefit of regression testing of test case sequence， a test case prioritization approach based on historical data and multi-objective optimization was proposed. Firstly， the test case set was clustered according to the text topic similarity and code coverage similarity of test cases， and the association rules were mined for execution failure relationships between test cases according to the historical execution information， thereby preparing for the subsequent process. Then， the multi-objective optimization algorithm was used to sort the test cases in each cluster. After that， the final sorting sequence was generated to separate the similar test cases. Finally， the association rules between test cases were used to dynamically adjust the execution order of test cases， so that the test cases that may fail were executed with priority， so as to further improve the efficiency of defect detection. Compared with random search approach， the approach based on clustering， the approach based on topic model， the approach based on association rules and multi-objective optimization， the proposed approach has the average value of Average Percentage of Faults Detected （APFD） increased by 12.59%， 5.98%， 3.01% and 2.95%， respectively， and has the average value of APFD cost-cognizant （APFDc） increased by 17.17%， 5.04%， 5.08% and 8.21%， respectively. Experimental results show that the proposed approach can improve the benefit of regression testing effectively.

Software defect prediction is a hot research topic in the field of software quality assurance. The quality of defect prediction models is closely related to the training data. The datasets used for defect prediction mainly have the problems of data feature selection and data class imbalance. Aiming at the problem of data feature selection, common process features of software development and the newly proposed extended process features were used, and then the feature selection algorithm based on clustering analysis was used to perform feature selection. Aiming at the data class imbalance problem, an improved Borderline-SMOTE (Borderline-Synthetic Minority Oversampling Technique) method was proposed to make the numbers of positive and negative samples in the training dataset relatively balanced, and make the characteristics of the synthesized samples more consistent with the actual sample characteristics. Experiments were performed by using the open source datasets of projects such as bugzilla and jUnit. The results show that the used feature selection algorithm can reduce the model training time by 57.94% while keeping high F-measure value of the model; compared to the defect prediction model obtained by using the original method to process samples, the model obtained by the improved Borderline-SMOTE method respectively increase the Precision, Recall, F-measure, and AUC (Area Under the Curve) by 2.36 percentage points, 1.8 percentage points, 2.13 percentage points and 2.36 percentage points on average; the defect prediction model obtained by introducing the extended process features has an average improvement of 3.79% in F-measure value compared to the model without the extended process features; compared with the models obtained by methods in the literatures, the model obtained by the proposed method has an average increase of 15.79% in F-measure value. The experimental results prove that the proposed method can effectively improve the quality of the defect prediction model.